Cargando…

The European Medicines Agency’s scientific opinion on oral fexinidazole for human African trypanosomiasis

Detalles Bibliográficos
Autores principales:	Pelfrene, Eric, Harvey Allchurch, Martin, Ntamabyaliro, Nsengi, Nambasa, Victoria, Ventura, Fátima V., Nagercoil, Nithyanandan, Cavaleri, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	From Innovation to Application
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597029/ https://www.ncbi.nlm.nih.gov/pubmed/31246956 http://dx.doi.org/10.1371/journal.pntd.0007381

Ejemplares similares

Kenya Trypanosomiasis Research Institute Cryobank for Human and Animal Trypanosome Isolates to Support Research: Opportunities and Challenges
por: Murilla, Grace A., et al.
Publicado: (2014)

Innovative Partnerships for the Elimination of Human African Trypanosomiasis and the Development of Fexinidazole
por: Neau, Philippe, et al.
Publicado: (2020)

Development and Introduction of Fexinidazole into the Global Human African Trypanosomiasis Program
por: Valverde Mordt, Olaf, et al.
Publicado: (2022)

Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership
por: Bernhard, Sonja, et al.
Publicado: (2022)

Efficacy and Toxicity of Fexinidazole and Nifurtimox Plus Eflornithine in the Treatment of African Trypanosomiasis: A Systematic Review
por: Hidalgo, Jessica, et al.
Publicado: (2021)

Modelling the impact of fexinidazole use on human African trypanosomiasis (HAT) transmission in the Democratic Republic of the Congo
por: Das, Aatreyee M., et al.
Publicado: (2021)

Discovery, Development, Inventions and Patent Review of Fexinidazole: The First All-Oral Therapy for Human African Trypanosomiasis
por: Imran, Mohd, et al.
Publicado: (2022)

Rapid, inexpensive, fingerstick, whole-blood, sensitive, specific, point-of-care test for anti-Toxoplasma antibodies
por: Lykins, Joseph, et al.
Publicado: (2018)

Determination of an Optimal Dosing Regimen for Fexinidazole, a Novel Oral Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Studies
por: Tarral, Antoine, et al.
Publicado: (2014)

Artemisinin-based combination therapy in the treatment of uncomplicated malaria: review of recent regulatory experience at the European Medicines Agency
por: Pelfrene, Eric, et al.
Publicado: (2015)

Improved PCR-RFLP for the Detection of Diminazene Resistance in Trypanosoma congolense under Field Conditions Using Filter Papers for Sample Storage
por: Vitouley, Hervé Sèna, et al.
Publicado: (2011)

An Innovative Database for Epidemiological Field Studies of Neglected Tropical Diseases
por: Gray, Darren J., et al.
Publicado: (2009)

A Global Public Database of Disease Vector and Reservoir Distributions
por: Moffett, Alexander, et al.
Publicado: (2009)

The Blueprint for Rabies Prevention and Control: A Novel Operational Toolkit for Rabies Elimination
por: Lembo, Tiziana
Publicado: (2012)

Improved Models of Mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for Sleeping Sickness Diagnosis and Staging
por: Büscher, Philippe, et al.
Publicado: (2009)

Interactive Multimedia to Teach the Life Cycle of Trypanosoma cruzi, the Causative Agent of Chagas Disease
por: Teixeira, Dirceu E., et al.
Publicado: (2012)

Detection of Viable Mycobacterium ulcerans in Clinical Samples by a Novel Combined 16S rRNA Reverse Transcriptase/IS2404 Real-Time qPCR Assay
por: Beissner, Marcus, et al.
Publicado: (2012)

Electronic Data Capture Tools for Global Health Programs: Evolution of LINKS, an Android-, Web-Based System
por: Pavluck, Alex, et al.
Publicado: (2014)

Parasite Load Decrease during Application of a Safe and Easily Applied Antileishmanial Aminoglycoside Cream
por: Salah, Afif Ben, et al.
Publicado: (2014)

Innovative Approaches to Clinical Data Management in Resource Limited Settings Using Open-Source Technologies
por: Omollo, Raymond, et al.
Publicado: (2014)

Potential Non-invasive Urine-Based Antigen (Protein) Detection Assay to Diagnose Active Visceral Leishmaniasis
por: Abeijon, Claudia, et al.
Publicado: (2013)

Resource Planning for Neglected Tropical Disease (NTD) Control Programs: Feasibility Study of the Tool for Integrated Planning and Costing (TIPAC)
por: Wouters, Olivier J., et al.
Publicado: (2014)

Development of a Biosensor-Based Rapid Urine Test for Detection of Urogenital Schistosomiasis
por: Mach, Kathleen E., et al.
Publicado: (2015)

Enhancing Decision Support for Vector-Borne Disease Control Programs—The Disease Data Management System
por: Thomsen, Edward K., et al.
Publicado: (2016)

Integrating Data and Resources on Neglected Tropical Diseases for Better Planning: The NTD Mapping Tool (NTDmap.org)
por: Flueckiger, Rebecca M., et al.
Publicado: (2015)

A Mobile Platform Enables Unprecedented Sanitation Uptake in Zambia
por: Markle, Laurie, et al.
Publicado: (2017)

Making Transmission Models Accessible to End-Users: The Example of TRANSFIL
por: Irvine, Michael A., et al.
Publicado: (2017)

OpenZika: An IBM World Community Grid Project to Accelerate Zika Virus Drug Discovery
por: Ekins, Sean, et al.
Publicado: (2016)

Biospecimen Repositories and Integrated Databases as Critical Infrastructure for Pathogen Discovery and Pathobiology Research
por: Dunnum, Jonathan L., et al.
Publicado: (2017)

DenvInt: A database of protein–protein interactions between dengue virus and its hosts
por: Dey, Lopamudra, et al.
Publicado: (2017)

Developing mobile health applications for neglected tropical disease research
por: Navarro, Andrés, et al.
Publicado: (2018)

Rapid and sensitive detection of Chlamydia trachomatis sexually transmitted infections in resource-constrained settings in Thailand at the point-of-care
por: Somboonna, Naraporn, et al.
Publicado: (2018)

A modified approach to recover and enumerate Ascaris ova in wastewater and sludge
por: Ravindran, Vivek B., et al.
Publicado: (2019)

Social media and control of soil-transmitted helminthiasis in Bhutan
por: Thinley, Sangay, et al.
Publicado: (2019)

MosqTent: An individual portable protective double-chamber mosquito trap for anthropophilic mosquitoes
por: Lima, José Bento Pereira, et al.
Publicado: (2017)

Preheating of urine improves the specificity of urinary cryptococcal antigen testing using the lateral flow assay
por: Brito-Santos, Fábio, et al.
Publicado: (2017)

Mobile-phone and handheld microscopy for neglected tropical diseases
por: Rajchgot, Jason, et al.
Publicado: (2017)

EbolaID: An Online Database of Informative Genomic Regions for Ebola Identification and Treatment
por: Carneiro, João, et al.
Publicado: (2016)

Oral fexinidazole for stage 1 or early stage 2 African Trypanosoma brucei gambiense trypanosomiasis: a prospective, multicentre, open-label, cohort study
por: Kande Betu Ku Mesu, Victor, et al.
Publicado: (2021)

Safety and efficacy of oral fexinidazole in children with gambiense human African trypanosomiasis: a multicentre, single-arm, open-label, phase 2–3 trial
por: Kande Betu Kumesu, Victor, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_popjkbus43go8uvhcb60a5vrd8