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Post genome-wide gene-environment interaction study: The effect of genetically driven insulin resistance on breast cancer risk using Mendelian randomization

PURPOSE: The role of insulin resistance (IR) in developing postmenopausal breast cancer has not been thoroughly resolved and may be confounded by lifestyle factors such as obesity. We examined whether genetically determined IR is causally associated with breast cancer risk. METHODS: We conducted Men...

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Detalles Bibliográficos
Autores principales: Jung, Su Yon, Mancuso, Nicholas, Papp, Jeanette, Sobel, Eric, Zhang, Zuo-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597082/
https://www.ncbi.nlm.nih.gov/pubmed/31246991
http://dx.doi.org/10.1371/journal.pone.0218917