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Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling

Glioblastoma is a high-grade glioma with poor prognosis even after surgery and standard therapy. Here, we asked whether carnosine (β-alanyl-L-histidine), a naturally occurring dipeptide, exert its anti-neoplastic effect on glioblastoma cells via PI3K/Akt/mTOR signaling. Therefore, glioblastoma cells...

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Detalles Bibliográficos
Autores principales: Oppermann, Henry, Faust, Helene, Yamanishi, Ulrike, Meixensberger, Jürgen, Gaunitz, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597087/
https://www.ncbi.nlm.nih.gov/pubmed/31247000
http://dx.doi.org/10.1371/journal.pone.0218972