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Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling
Glioblastoma is a high-grade glioma with poor prognosis even after surgery and standard therapy. Here, we asked whether carnosine (β-alanyl-L-histidine), a naturally occurring dipeptide, exert its anti-neoplastic effect on glioblastoma cells via PI3K/Akt/mTOR signaling. Therefore, glioblastoma cells...
Autores principales: | Oppermann, Henry, Faust, Helene, Yamanishi, Ulrike, Meixensberger, Jürgen, Gaunitz, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597087/ https://www.ncbi.nlm.nih.gov/pubmed/31247000 http://dx.doi.org/10.1371/journal.pone.0218972 |
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