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Is urinary excretion of plasminogen associated with development of pre-eclampsia? An observational, explorative case–control study

OBJECTIVES: Pre-eclampsia (PE) is characterised by renal glomerular endotheliosis and injury to the glomerular filtration barrier with proteinuria. Patients with PE display aberrant filtration of the plasma proenzyme plasminogen which is activated, in the tubular fluid, to plasmin. Plasmin may activ...

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Detalles Bibliográficos
Autores principales: Nielsen, Lise H, Kronborg, Camilla, Vittinghus, Erik, Kitlen, Gitte, Jensen, Boye L, Knudsen, Ulla B, Ovesen, Per G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597096/
https://www.ncbi.nlm.nih.gov/pubmed/31230006
http://dx.doi.org/10.1136/bmjopen-2018-026489