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DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes

DNA methylation is pervasive across all domains of life. In bacteria, the presence of N6-methyladenosine (m6A) has been detected among diverse species, yet the contribution of m6A to the regulation of gene expression is unclear in many organisms. Here we investigated the impact of DNA methylation on...

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Detalles Bibliográficos
Autores principales: Nye, Taylor M., Jacob, Kristin M., Holley, Elena K., Nevarez, Juan M., Dawid, Suzanne, Simmons, Lyle A., Watson, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597129/
https://www.ncbi.nlm.nih.gov/pubmed/31206562
http://dx.doi.org/10.1371/journal.ppat.1007841