A Rare Double Primary Tumor of the Pancreas and the Esophagus

Primary pancreatic cancer with synchronous primary tumors from other organs is extremely rare. Hereditary conditions, such as Lynch syndrome, Peutz-Jeghers syndrome, and hereditary pancreatitis, are linked to 10% of pancreatic cancers and may increase the risk of secondary malignancies from other organs. Only three cases of synchronous cancers of the pancreas and esophagus have been reported in the literature. Interestingly, patients with double primary tumors have been observed to have better overall survival than those with pancreatic cancers alone. We report the fourth such case of a 54-year-old male diagnosed with a double primary cancer of the pancreas and the esophagus diagnosed with endoscopic ultrasound (EUS).