Identification and Characterization of Two Novel Oncogenic mTOR Mutations

Mammalian target of rapamycin (mTOR) signaling is often aberrantly activated, particularly when genetically activated, in human cancers. mTOR inhibitors targeting the activated mTOR signaling are highly promising anti-cancer drugs. Knowing the activating genetic change in mTOR can help guide the use...

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Detalles Bibliográficos
Autores principales: Murugan, Avaniyapuram Kannan, Liu, Rengyun, Xing, Mingzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597304/
https://www.ncbi.nlm.nih.gov/pubmed/30918329
http://dx.doi.org/10.1038/s41388-019-0787-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597304/
https://www.ncbi.nlm.nih.gov/pubmed/30918329
http://dx.doi.org/10.1038/s41388-019-0787-5

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