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Identification and Characterization of Two Novel Oncogenic mTOR Mutations
Mammalian target of rapamycin (mTOR) signaling is often aberrantly activated, particularly when genetically activated, in human cancers. mTOR inhibitors targeting the activated mTOR signaling are highly promising anti-cancer drugs. Knowing the activating genetic change in mTOR can help guide the use...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597304/ https://www.ncbi.nlm.nih.gov/pubmed/30918329 http://dx.doi.org/10.1038/s41388-019-0787-5 |