Central nervous system regeneration is driven by microglia necroptosis and repopulation

Failed regeneration of central nervous system myelin contributes to clinical decline in neuroinflammatory and neurodegenerative diseases, for which there is an unmet therapeutic need. Here, we reveal that efficient remyelination requires death of pro-inflammatory microglia followed by repopulation t...

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Detalles Bibliográficos
Autores principales: Lloyd, Amy F., Davies, Claire L., Holloway, Rebecca K., Labrak, Yasmine, Ireland, Graeme, Carradori, Dario, Dillenburg, Alessandra, Borger, Eva, Soong, Daniel, Richardson, Jill C., Kuhlmann, Tanja, Williams, Anna, Pollard, Jeffrey W., des Rieux, Anne, Priller, Josef, Miron, Veronique E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597360/
https://www.ncbi.nlm.nih.gov/pubmed/31182869
http://dx.doi.org/10.1038/s41593-019-0418-z

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