Cargando…

Doxorubicin Promotes Migration and Invasion of Breast Cancer Cells through the Upregulation of the RhoA/MLC Pathway

PURPOSE: Cancer cells develop acquired resistance induced by chemotherapeutic drugs. In this study, we investigated the effects of brief treatment with cytotoxic drugs on the phenotype of breast cancer cells. METHODS: Breast cancer cells MCF7 and BT-474 were briefly treated with paclitaxel or doxoru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Chien-Liang, Chen, Ming-Jen, Lin, Jiunn-Chang, Lin, Chi-Hsin, Huang, Wen-Chien, Cheng, Shih-Ping, Chen, Shan-Na, Chang, Yuan-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Breast Cancer Society 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597404/ https://www.ncbi.nlm.nih.gov/pubmed/31281722 http://dx.doi.org/10.4048/jbc.2019.22.e22

Ejemplares similares

O-GlcNAcylation promotes migration and invasion in human ovarian cancer cells via the RhoA/ROCK/MLC pathway
por: Niu, Yichao, et al.
Publicado: (2017)

MiR-31 Regulates Rho-Associated Kinase-Myosin Light Chain (ROCK-MLC) Pathway and Inhibits Gastric Cancer Invasion: Roles of RhoA
por: Chen, Zhuo, et al.
Publicado: (2016)

Dynamic functions of RhoA in tumor cell migration and invasion
por: O'Connor, Kathleen, et al.
Publicado: (2013)

Pennogenin Tetraglycoside Induces Rat Myometrial Contraction and MLC20 Phosphorylation via PLC-IP(3) and RhoA/Rho Kinase Signaling Pathways
por: Wang, Limei, et al.
Publicado: (2012)

Porcine Sapovirus-Induced Tight Junction Dissociation via Activation of the RhoA/ROCK/MLC Signaling Pathway
por: Sharif, Muhammad, et al.
Publicado: (2021)

RhoA/Rho-Kinase and Nitric Oxide in Vascular Reactivity in Rats with Endotoxaemia
por: Liao, Mei-Hui, et al.
Publicado: (2013)

RhoA/ROCK1 regulates Avian Reovirus S1133-induced switch from autophagy to apoptosis
por: Lin, Ping-Yuan, et al.
Publicado: (2015)

QiShenYiQi Pills Attenuates Ischemia/Reperfusion-Induced Cardiac Microvascular Hyperpermeability Implicating Src/Caveolin-1 and RhoA/ROCK/MLC Signaling
por: Pan, Chun-Shui, et al.
Publicado: (2021)

Activation of mTOR mediates hyperglycemia-induced renal glomerular endothelial hyperpermeability via the RhoA/ROCK/pMLC signaling pathway
por: Chen, Xiaolin, et al.
Publicado: (2021)

RhoA improves cryopreservation of rooster sperm through the Rho/RhoA-associated kinase/cofilin pathway
por: Heng, Nuo, et al.
Publicado: (2022)

RhoA Controls Wnt Upregulation on Microstructured Titanium Surfaces
por: Lumetti, Simone, et al.
Publicado: (2014)

Herb-Partitioned Moxibustion Improves Crohn's Disease-Associated Intestinal Fibrosis by Suppressing the RhoA/ROCK1/MLC Pathway
por: Zhao, Min, et al.
Publicado: (2021)

Extracellular heat shock protein 90α mediates HDM-induced bronchial epithelial barrier dysfunction by activating RhoA/MLC signaling
por: Dong, Hang-ming, et al.
Publicado: (2017)

High Glucose Aggravates Retinal Endothelial Cell Dysfunction by Activating the RhoA/ROCK1/pMLC/Connexin43 Signaling Pathway
por: Zhao, Hongran, et al.
Publicado: (2022)

Thy-1-Induced Migration Inhibition in Vascular Endothelial Cells through Reducing the RhoA Activity
por: Wen, Heng-Ching, et al.
Publicado: (2013)

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets
por: Vega, Francisco M., et al.
Publicado: (2011)

Thrombin induces IL-8/CXCL8 expression by DCLK1-dependent RhoA and YAP activation in human lung epithelial cells
por: Yuliani, Fara Silvia, et al.
Publicado: (2022)

Rotavirus-Induced Early Activation of the RhoA/ROCK/MLC Signaling Pathway Mediates the Disruption of Tight Junctions in Polarized MDCK Cells
por: Soliman, Mahmoud, et al.
Publicado: (2018)

ANLN Directly Interacts with RhoA to Promote Doxorubicin Resistance in Breast Cancer Cells
por: Wang, Feng, et al.
Publicado: (2020)

Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling
por: Wang, Jing, et al.
Publicado: (2020)

A RhoC Biosensor Reveals Differences in the Activation Kinetics of RhoA and RhoC in Migrating Cells
por: Zawistowski, Jon S., et al.
Publicado: (2013)

The role of RhoA/Rho kinase pathway in endothelial dysfunction
por: Yao, Lin, et al.
Publicado: (2010)

Fibroblast Activation Protein (FAP) Is Essential for the Migration of Bone Marrow Mesenchymal Stem Cells through RhoA Activation
por: Chung, Kuei-Min, et al.
Publicado: (2014)

Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
por: Zhang, Jason Z., et al.
Publicado: (2020)

RhoA is required for monocyte tail retraction during transendothelial migration
por: Worthylake, Rebecca A., et al.
Publicado: (2001)

Nicorandil regulates the macrophage skewing and ameliorates myofibroblasts by inhibition of RhoA/Rho‐kinase signalling in infarcted rats
por: Lee, Tsung‐Ming, et al.
Publicado: (2017)

RhoA/Rho kinase in spinal cord injury
por: Wu, Xiangbing, et al.
Publicado: (2016)

Quinolinate Phosphoribosyltransferase Promotes Invasiveness of Breast Cancer Through Myosin Light Chain Phosphorylation
por: Liu, Chien-Liang, et al.
Publicado: (2021)

Deleted in Liver Cancer 1 (DLC1) Negatively Regulates Rho/ROCK/MLC Pathway in Hepatocellular Carcinoma
por: Wong, Carmen Chak-Lui, et al.
Publicado: (2008)

The diagnostic and prognostic role of RhoA in hepatocellular carcinoma
por: Bai, Yi, et al.
Publicado: (2019)

Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle
por: Mahavadi, Sunila, et al.
Publicado: (2017)

RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes
por: Jackson, Ben, et al.
Publicado: (2011)

Protocol for structural and biochemical analyses of RhoA GTPase
por: Lin, Yuan, et al.
Publicado: (2021)

Protein Kinase A Governs a RhoA-RhoGDI Protrusion-Retraction Pacemaker in Migrating Cells
por: Tkachenko, Eugene, et al.
Publicado: (2011)

Regulation of RhoA-dependent ROCKII activation by Shp2
por: Lee, Hsiao-Hui, et al.
Publicado: (2008)

RhoA controls furrow formation
por: Tuma, Rabiya S.
Publicado: (2005)

RhoA brings up the rear
por: Dove, Alan W.
Publicado: (2001)

Complementary receptors control RhoA
por: Robinson, Richard
Publicado: (2008)

RhoA Regulation of Cardiomyocyte Differentiation
por: Kaarbø, Mari, et al.
Publicado: (2013)

RhoA in aneurysmal subarachnoid hemorrhage
por: Ureña, Juan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rrvorn4ofhefl4ilkedd4img1n