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p62 Negatively Regulates TLR4 Signaling via Functional Regulation of the TRAF6-ECSIT Complex

Sequestosome 1 (SQSTM1, p62), a ubiquitin binding protein, plays a role in cell signaling, oxidative stress, and autophagy. However, its functional role in inflammatory signaling is controversial. Recent studies have shown that p62 is negatively implicated in inflammatory responses. But, the precise...

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Detalles Bibliográficos
Autores principales: Kim, Mi-Jeong, Min, Yoon, Kwon, Jeongho, Son, Juhee, Im, Ji Seon, Shin, Jaekyoon, Lee, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597446/
https://www.ncbi.nlm.nih.gov/pubmed/31281713
http://dx.doi.org/10.4110/in.2019.19.e16