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De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation
Transdifferentiation is a complete and stable change in cell identity that serves as an alternative to stem-cell-mediated organ regeneration. In adult mammals, findings of transdifferentiation have been limited to the replenishment of cells lost from preexisting structures, i.e., in the presence of...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597492/ https://www.ncbi.nlm.nih.gov/pubmed/29720662 http://dx.doi.org/10.1038/s41586-018-0075-5 |