De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation

Transdifferentiation is a complete and stable change in cell identity that serves as an alternative to stem-cell-mediated organ regeneration. In adult mammals, findings of transdifferentiation have been limited to the replenishment of cells lost from preexisting structures, i.e., in the presence of...

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Detalles Bibliográficos
Autores principales: Schaub, Johanna R., Huppert, Kari A., Kurial, Simone N. T., Hsu, Bernadette Y., Cast, Ashley E., Donnelly, Bryan, Karns, Rebekah A., Chen, Feng, Rezvani, Milad, Luu, Hubert Y., Mattis, Aras N., Rougemont, Anne-Laure, Rosenthal, Philip, Huppert, Stacey S., Willenbring, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597492/
https://www.ncbi.nlm.nih.gov/pubmed/29720662
http://dx.doi.org/10.1038/s41586-018-0075-5

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