GSTM1, GSTT1 and GSTP1 Ile105Val polymorphisms in outcomes of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation

Cisplatin (CDDP) combined with radiotherapy (RT) is employed in head and neck squamous cell carcinoma (HNSCC) with variable toxicities and clinical response. Glutathione S-transferases (GSTs) participate in CDDP excretion from cells, and genes encoding GSTs, GSTM1, GSTT1and GSTP1, are polymorphic in...

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Detalles Bibliográficos
Autores principales: Pincinato, Eder C., Costa, Ericka F. D., Lopes-Aguiar, Leisa, Nogueira, Guilherme A. S., Lima, Tathiane R. P., Visacri, Marília B., Costa, Anna P. L., Lourenço, Gustavo J., Calonga, Luciane, Mariano, Fernanda V., Altemani, Albina M. A. M., Coutinho-Camillo, Cláudia, Chone, Carlos T., Ramos, Celso D., Altemani, João M. C., Moriel, Patrícia, Lima, Carmen S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597539/
https://www.ncbi.nlm.nih.gov/pubmed/31249357
http://dx.doi.org/10.1038/s41598-019-45808-6

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