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Enrichment of intestinal Lactobacillus by enhanced secretory IgA coating alters glucose homeostasis in P2rx7(−/−) mice

The secretory immunoglobulin A (SIgA) in mammalian gut protects the organism from infections and contributes to host physiology by shaping microbiota composition. The mechanisms regulating the adaptive SIgA response towards gut microbes are poorly defined. Deletion of P2rx7, encoding for the ATP-gat...

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Detalles Bibliográficos
Autores principales: Perruzza, Lisa, Strati, Francesco, Gargari, Giorgio, D’Erchia, Anna Maria, Fosso, Bruno, Pesole, Graziano, Guglielmetti, Simone, Grassi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597561/
https://www.ncbi.nlm.nih.gov/pubmed/31249344
http://dx.doi.org/10.1038/s41598-019-45724-9