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Enrichment of intestinal Lactobacillus by enhanced secretory IgA coating alters glucose homeostasis in P2rx7(−/−) mice
The secretory immunoglobulin A (SIgA) in mammalian gut protects the organism from infections and contributes to host physiology by shaping microbiota composition. The mechanisms regulating the adaptive SIgA response towards gut microbes are poorly defined. Deletion of P2rx7, encoding for the ATP-gat...
Autores principales: | Perruzza, Lisa, Strati, Francesco, Gargari, Giorgio, D’Erchia, Anna Maria, Fosso, Bruno, Pesole, Graziano, Guglielmetti, Simone, Grassi, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597561/ https://www.ncbi.nlm.nih.gov/pubmed/31249344 http://dx.doi.org/10.1038/s41598-019-45724-9 |
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