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FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype

Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that requires novel therapies in the advanced setting. To study acquired resistance to endocrine therapy in ILC, we have recently performed RNA-Sequencing on long-term estrogen deprived cell lines and identified FGFR4 overe...

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Detalles Bibliográficos
Autores principales: Levine, Kevin M., Priedigkeit, Nolan, Basudan, Ahmed, Tasdemir, Nilgun, Sikora, Matthew J., Sokol, Ethan S., Hartmaier, Ryan J., Ding, Kai, Ahmad, Nedah Z., Watters, Rebecca J., Weiss, Kurt R., Blohmer, Jens-Uwe, Denkert, Carsten, Machleidt, Anna, Karsten, Maria M., Boisen, Michelle M., Elishaev, Esther, Lucas, Peter C., Lee, Adrian V., Oesterreich, Steffi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597581/
https://www.ncbi.nlm.nih.gov/pubmed/31263748
http://dx.doi.org/10.1038/s41523-019-0114-x

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