Cargando…
FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that requires novel therapies in the advanced setting. To study acquired resistance to endocrine therapy in ILC, we have recently performed RNA-Sequencing on long-term estrogen deprived cell lines and identified FGFR4 overe...
Autores principales: | Levine, Kevin M., Priedigkeit, Nolan, Basudan, Ahmed, Tasdemir, Nilgun, Sikora, Matthew J., Sokol, Ethan S., Hartmaier, Ryan J., Ding, Kai, Ahmad, Nedah Z., Watters, Rebecca J., Weiss, Kurt R., Blohmer, Jens-Uwe, Denkert, Carsten, Machleidt, Anna, Karsten, Maria M., Boisen, Michelle M., Elishaev, Esther, Lucas, Peter C., Lee, Adrian V., Oesterreich, Steffi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597581/ https://www.ncbi.nlm.nih.gov/pubmed/31263748 http://dx.doi.org/10.1038/s41523-019-0114-x |
Ejemplares similares
-
Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer
por: Du, Tian, et al.
Publicado: (2018) -
Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences
por: Priedigkeit, Nolan, et al.
Publicado: (2021) -
Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer
por: Sokol, E S, et al.
Publicado: (2019) -
Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism
por: Du, Tian, et al.
Publicado: (2018) -
Proteomic and transcriptomic profiling identifies mediators of anchorage-independent growth and roles of inhibitor of differentiation proteins in invasive lobular carcinoma
por: Tasdemir, Nilgun, et al.
Publicado: (2020)