A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys

Defining cellular and molecular identities within the kidney is necessary to understand its organization and function in health and disease. Here we demonstrate a reproducible method with minimal artifacts for single-nucleus Droplet-based RNA sequencing (snDrop-Seq) that we use to resolve thirty dis...

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Detalles Bibliográficos
Autores principales: Lake, Blue B., Chen, Song, Hoshi, Masato, Plongthongkum, Nongluk, Salamon, Diane, Knoten, Amanda, Vijayan, Anitha, Venkatesh, Ramakrishna, Kim, Eric H., Gao, Derek, Gaut, Joseph, Zhang, Kun, Jain, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597610/
https://www.ncbi.nlm.nih.gov/pubmed/31249312
http://dx.doi.org/10.1038/s41467-019-10861-2

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