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Sleep-Cognition Hypothesis In maritime Pilots, what is the effect of long-term work-related poor sleep on cognition and amyloid accumulation in healthy middle-aged maritime pilots: methodology of a case–control study
INTRODUCTION: Evidence indicates a bidirectional relationship between poor sleep and Alzheimer’s disease (AD). While AD may lead to disruption of normal sleep, poor sleep in itself may play a causal role in the development of AD by influencing the production and/or clearance of the amyloid-beta (Aβ)...
Autores principales: | Thomas, Jana, Ooms, Sharon, Verbeek, Marcel, Booij, Jan, Rijpkema, Mark, Kessels, Roy P C, Overeem, Sebastiaan, Claassen, Jurgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597630/ https://www.ncbi.nlm.nih.gov/pubmed/31248923 http://dx.doi.org/10.1136/bmjopen-2018-026992 |
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