Skin Carotenoid Index in a large Japanese population sample

Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients an...

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Autores principales: Obana, Akira, Gohto, Yuko, Gellermann, Werner, Ermakov, Igor V., Sasano, Hiroyuki, Seto, Takahiko, Bernstein, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597710/
https://www.ncbi.nlm.nih.gov/pubmed/31249340
http://dx.doi.org/10.1038/s41598-019-45751-6
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author Obana, Akira
Gohto, Yuko
Gellermann, Werner
Ermakov, Igor V.
Sasano, Hiroyuki
Seto, Takahiko
Bernstein, Paul S.
author_facet Obana, Akira
Gohto, Yuko
Gellermann, Werner
Ermakov, Igor V.
Sasano, Hiroyuki
Seto, Takahiko
Bernstein, Paul S.
author_sort Obana, Akira
collection PubMed
description Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of an ophthalmology clinic (577 men, 408 women, mean age of 69.7 ± 13.6 [SD]). Skin carotenoid (SC) and macular pigment (MP) levels were measured with reflection spectroscopy and autofluorescence imaging methods, respectively. The mean SC index was 343.1 ± 142.1 (SD). SC indices for women were higher than for men (382 vs 315, p < 0.001). Smokers and overweight subjects (BMI ≥ 25) had lower SC indices. Subjects taking lutein supplements had higher SC indices than non-supplementing subjects (415 vs 325, p < 0.001). SC and MP indices were significantly correlated. The obtained data set can be used for reference purposes by Japanese subjects and researchers interested in tissue responses to diets high in carotenoids and lutein supplementation.
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spelling pubmed-65977102019-07-09 Skin Carotenoid Index in a large Japanese population sample Obana, Akira Gohto, Yuko Gellermann, Werner Ermakov, Igor V. Sasano, Hiroyuki Seto, Takahiko Bernstein, Paul S. Sci Rep Article Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of an ophthalmology clinic (577 men, 408 women, mean age of 69.7 ± 13.6 [SD]). Skin carotenoid (SC) and macular pigment (MP) levels were measured with reflection spectroscopy and autofluorescence imaging methods, respectively. The mean SC index was 343.1 ± 142.1 (SD). SC indices for women were higher than for men (382 vs 315, p < 0.001). Smokers and overweight subjects (BMI ≥ 25) had lower SC indices. Subjects taking lutein supplements had higher SC indices than non-supplementing subjects (415 vs 325, p < 0.001). SC and MP indices were significantly correlated. The obtained data set can be used for reference purposes by Japanese subjects and researchers interested in tissue responses to diets high in carotenoids and lutein supplementation. Nature Publishing Group UK 2019-06-27 /pmc/articles/PMC6597710/ /pubmed/31249340 http://dx.doi.org/10.1038/s41598-019-45751-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Obana, Akira
Gohto, Yuko
Gellermann, Werner
Ermakov, Igor V.
Sasano, Hiroyuki
Seto, Takahiko
Bernstein, Paul S.
Skin Carotenoid Index in a large Japanese population sample
title Skin Carotenoid Index in a large Japanese population sample
title_full Skin Carotenoid Index in a large Japanese population sample
title_fullStr Skin Carotenoid Index in a large Japanese population sample
title_full_unstemmed Skin Carotenoid Index in a large Japanese population sample
title_short Skin Carotenoid Index in a large Japanese population sample
title_sort skin carotenoid index in a large japanese population sample
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597710/
https://www.ncbi.nlm.nih.gov/pubmed/31249340
http://dx.doi.org/10.1038/s41598-019-45751-6
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