Effect of Leptin Deficiency on the Skeletal Response to Hindlimb Unloading in Adult Male Mice

Based on body weight, morbidly obese leptin-deficient ob/ob mice have less bone than expected, suggesting that leptin plays a role in the skeletal response to weight bearing. To evaluate this possibility, we compared the skeletal response of wild type (WT) and ob/ob mice to hindlimb unloading (HU)....

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Detalles Bibliográficos
Autores principales: Keune, Jessica A., Branscum, Adam J., Wong, Carmen P., Iwaniec, Urszula T., Turner, Russell T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597714/
https://www.ncbi.nlm.nih.gov/pubmed/31249331
http://dx.doi.org/10.1038/s41598-019-45587-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597714/
https://www.ncbi.nlm.nih.gov/pubmed/31249331
http://dx.doi.org/10.1038/s41598-019-45587-0

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