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Effect of Leptin Deficiency on the Skeletal Response to Hindlimb Unloading in Adult Male Mice
Based on body weight, morbidly obese leptin-deficient ob/ob mice have less bone than expected, suggesting that leptin plays a role in the skeletal response to weight bearing. To evaluate this possibility, we compared the skeletal response of wild type (WT) and ob/ob mice to hindlimb unloading (HU)....
Autores principales: | Keune, Jessica A., Branscum, Adam J., Wong, Carmen P., Iwaniec, Urszula T., Turner, Russell T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597714/ https://www.ncbi.nlm.nih.gov/pubmed/31249331 http://dx.doi.org/10.1038/s41598-019-45587-0 |
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