Human glutathione-S-transferase pi potentiates the cysteine-protease activity of the Der p 1 allergen from house dust mite through a cysteine redox mechanism

Environmental proteases have been widely associated to the pathogenesis of allergic disorders. Der p 1, a cysteine-protease from house dust mite (HDM) Dermatophagoides pteronyssinus, constitutes one of the most clinically relevant indoor aeroallergens worldwide. Der p 1 protease activity depends on...

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Detalles Bibliográficos
Autores principales: López-Rodríguez, Juan Carlos, Manosalva, Juliana, Cabrera-García, J. Daniel, Escribese, María M., Villalba, Mayte, Barber, Domingo, Martínez-Ruiz, Antonio, Batanero, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597738/
https://www.ncbi.nlm.nih.gov/pubmed/31229842
http://dx.doi.org/10.1016/j.redox.2019.101256

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