Neurovascular protection in voltage‐gated proton channel Hv1 knock‐out rats after ischemic stroke: interaction with Na(+)/H(+) exchanger‐1 antagonism

Experimental studies have demonstrated protective effects of NHE‐1 inhibition on cardiac function; however, clinical trials utilizing NHE‐1 antagonists found an increase in overall mortality attributed to thromboembolic strokes. NADPH oxidase‐derived reactive oxygen species (ROS) from microglial cel...

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Detalles Bibliográficos
Autores principales: Li, Weiguo, Ward, Rebecca, Dong, Guangkuo, Ergul, Adviye, O'Connor, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597793/
https://www.ncbi.nlm.nih.gov/pubmed/31250553
http://dx.doi.org/10.14814/phy2.14142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597793/
https://www.ncbi.nlm.nih.gov/pubmed/31250553
http://dx.doi.org/10.14814/phy2.14142

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