Cargando…

Metformin modulates immune cell infiltration into the kidney during unilateral ureteral obstruction in mice

Metformin is today the first choice treatment for type‐2 diabetes, but has also protective effects in several renal disease models. Previously, we have demonstrated that the protective effects in response to unilateral ureteral obstruction (UUO) are independent of organic cation transporters (OCTs),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Christensen, Michael, Nørgård, Mikkel Ø., Jensen, Michael S., Møller, Bjarne K., Nørregaard, Rikke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597795/ https://www.ncbi.nlm.nih.gov/pubmed/31250538 http://dx.doi.org/10.14814/phy2.14141

Ejemplares similares

Phenformin Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice without Affecting Immune Cell Infiltration
por: Nørgård, Mikkel Ø., et al.
Publicado: (2020)

Activation of the prostaglandin E(2) EP(2) receptor attenuates renal fibrosis in unilateral ureteral obstructed mice and human kidney slices
por: Jensen, Michael Schou, et al.
Publicado: (2019)

P2X(7) accelerate tissue fibrosis via metalloproteinase 8‐dependent macrophage infiltration in a murine model of unilateral ureteral obstruction
por: Therkildsen, Jacob Rudjord, et al.
Publicado: (2023)

Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice
por: Yang, Chuanxu, et al.
Publicado: (2015)

Matrix Metalloproteinase-2 Knockout and Heterozygote Mice Are Protected from Hydronephrosis and Kidney Fibrosis after Unilateral Ureteral Obstruction
por: Tveitarås, Maria K., et al.
Publicado: (2015)

DAMPs in Unilateral Ureteral Obstruction
por: Wyczanska, Maja, et al.
Publicado: (2020)

15-Deoxy-Δ(12,14)-prostaglandin J(2) Exerts Antioxidant Effects While Exacerbating Inflammation in Mice Subjected to Ureteral Obstruction
por: Nilsson, Line, et al.
Publicado: (2017)

Metformin attenuates renal interstitial fibrosis through upregulation of Deptor in unilateral ureteral obstruction in rats
por: Wang, Yanxia, et al.
Publicado: (2020)

Verbascoside alleviates renal fibrosis in unilateral ureteral obstruction rats by inhibiting macrophage infiltration
por: Zhang, Guihua, et al.
Publicado: (2021)

Effects of exendin-4 on the intrarenal renin-angiotensin system and interstitial fibrosis in unilateral ureteral obstruction mice: Exendin-4 and unilateral ureteral obstruction
por: Le, Ying, et al.
Publicado: (2016)

Kidney-Draining Lymph Node Fibrosis Following Unilateral Ureteral Obstruction
por: Li, Xiaofei, et al.
Publicado: (2021)

Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts
por: Shen, Yang, et al.
Publicado: (2016)

siRNA-silencing of CD40 attenuates unilateral ureteral obstruction-induced kidney injury in mice
por: Narváez, Alonso, et al.
Publicado: (2019)

Bilateral Ureteral Obstruction Causing Acute Kidney Injury and Resultant Metformin Toxicity
por: Rashid, Umar, et al.
Publicado: (2021)

Expression of Aquaporin-3 in Ipsilateral Rat Kidney With Unilateral Partial Ureteral Obstruction
por: Lee, Ji Yong, et al.
Publicado: (2013)

Kidney Tissue Targeted Metabolic Profiling of Unilateral Ureteral Obstruction Rats by NMR
por: Li, Zhenyu, et al.
Publicado: (2016)

Effect of ipsilateral ureteric obstruction on contralateral kidney and role of renin angiotensin system blockade on renal recovery in experimentally induced unilateral ureteric obstruction
por: Panda, Shasanka S., et al.
Publicado: (2013)

Effects of melatonin on partial unilateral ureteral obstruction induced oxidative injury in rat kidney
por: Atılgan, Dogan, et al.
Publicado: (2012)

Increased adenosine levels contribute to ischemic kidney fibrosis in the unilateral ureteral obstruction model
por: TANG, JIN, et al.
Publicado: (2015)

Mass Spectrometry Imaging of Kidney Tissue Sections of Rat Subjected to Unilateral Ureteral Obstruction
por: Liu, Huihui, et al.
Publicado: (2017)

Melatonin protects kidney against apoptosis induced by acute unilateral ureteral obstruction in rats
por: Yildirim, Mehmet Erol, et al.
Publicado: (2016)

A modified relief of unilateral ureteral obstruction model
por: Song, Jie, et al.
Publicado: (2019)

Increased Phosphorylation of PI3K/Akt/mTOR in the Obstructed Kidney of Rats with Unilateral Ureteral Obstruction
por: Ma, Seong Kwon, et al.
Publicado: (2013)

Iron Chelation by Deferoxamine Prevents Renal Interstitial Fibrosis in Mice with Unilateral Ureteral Obstruction
por: Ikeda, Yasumasa, et al.
Publicado: (2014)

Diminazene aceturate exacerbates renal fibrosis after unilateral ureteral obstruction in female mice
por: Kim, Yosep, et al.
Publicado: (2023)

Deletion of Akt1 Promotes Kidney Fibrosis in a Murine Model of Unilateral Ureteral Obstruction
por: Kim, Il Young, et al.
Publicado: (2020)

The antifibrotic and anti-inflammatory effects of FZHY prescription on the kidney in rats after unilateral ureteral obstruction
por: Chen, Ziwei, et al.
Publicado: (2023)

Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney
por: Christensen, Michael, et al.
Publicado: (2016)

The contralateral kidney presents with impaired mitochondrial functions and disrupted redox homeostasis after 14 days of unilateral ureteral obstruction in mice
por: Bianco, Mario, et al.
Publicado: (2019)

Renal recruitment of B lymphocytes exacerbates tubulointerstitial fibrosis by promoting monocyte mobilization and infiltration after unilateral ureteral obstruction
por: Han, Hui, et al.
Publicado: (2016)

Renoprotection against complete unilateral ureteric obstruction: Is there an ultimate choice?
por: Khalil, Khaled I., et al.
Publicado: (2012)

Development of a unilateral ureteral obstruction model in cynomolgus monkeys
por: Huang, Linghong, et al.
Publicado: (2021)

Alpha-lipoic acid ameliorates the epithelial mesenchymal transition induced by unilateral ureteral obstruction in mice
por: Cho, Hyun Seop, et al.
Publicado: (2017)

Renal developmental genes are differentially regulated after unilateral ureteral obstruction in neonatal and adult mice
por: Kubik, Melanie J., et al.
Publicado: (2020)

Screening and identification of the differentially expressed proteins in neonatal rat kidney after partial unilateral ureteral obstruction
por: ZHAO, QI, et al.
Publicado: (2016)

Protective effects of SKLB023 on a mouse model of unilateral ureteral obstruction by the modulation of gut microbiota
por: Feng, Yanhuan, et al.
Publicado: (2018)

Simplified Stereological Evaluation of Renal Morphology after Unilateral Ureteral Obstruction
por: Hu, Peng, et al.
Publicado: (2013)

Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and Hematuria
por: Acar, Ömer, et al.
Publicado: (2013)

The Effect of Arabic Gum on Renal Function in Reversible Unilateral Ureteric Obstruction
por: Hammad, Fayez T., et al.
Publicado: (2019)

FFNT25 ameliorates unilateral ureteral obstruction-induced renal fibrosis
por: Li, Wen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_g4i1nuuabjc8gqud1uav5v8eqh