Sickling-preventive effects of rutin is associated with modulation of deoxygenated haemoglobin, 2,3-bisphosphoglycerate mutase, redox status and alteration of functional chemistry in sickle erythrocytes

Sickle cell anaemia is a hereditary disease branded by an upsurge in generation of ROS, irregular iron release and little or no antioxidant activity which can lead to cellular injuries due to oxidative stress resulting in severe symptoms including anaemia and pain. The disease is caused by a mutated...

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Detalles Bibliográficos
Autores principales: Muhammad, Aliyu, Waziri, Aliyu Dahiru, Forcados, Gilead Ebiegberi, Sanusi, Babangida, Sani, Hadiza, Malami, Ibrahim, Abubakar, Ibrahim Babangida, Oluwatoyin, Habeebah Yahya, Adinoyi, Otaru Abdulrasheed, Mohammed, Hafsat Abdullahi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597891/
https://www.ncbi.nlm.nih.gov/pubmed/31297461
http://dx.doi.org/10.1016/j.heliyon.2019.e01905

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