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A 24-week double-blind placebo-controlled study of the efficacy and safety of the AMPA modulator S47445 in patients with mild to moderate Alzheimer's disease and depressive symptoms

INTRODUCTION: S47445 is a novel positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptors that may emerge as a favorable candidate for the symptomatic treatment of cognitive and depressive disorders in patients suffering from Alzheimer's disease (AD) o...

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Detalles Bibliográficos
Autores principales:	Bernard, Katy, Gouttefangeas, Sylvie, Bretin, Sylvie, Galtier, Stéphanie, Robert, Philippe, Holthoff-Detto, Vjera, Cummings, Jeffrey, Pueyo, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Featured Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597919/ https://www.ncbi.nlm.nih.gov/pubmed/31297437 http://dx.doi.org/10.1016/j.trci.2019.04.002

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