Cargando…

Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibility

Altered reproductive hormone levels have been associated with the pathophysiology of depressive disorders and this risk may be imparted by their modulatory effect upon hippocampal structure and function. Currently it is unclear whether altered levels of reproductive hormones are causally associated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smeeth, Demelza M., Dima, Danai, Jones, Lisa, Jones, Ian, Craddock, Nick, Owen, Michael J, Rietschel, Marcella, Maier, Wolfgang, Korszun, Ania, Rice, John P., Mors, Ole, Preisig, Martin, Uher, Rudolf, Lewis, Cathryn M., Thuret, Sandrine, Powell, Timothy R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pergamon Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597945/ https://www.ncbi.nlm.nih.gov/pubmed/31039525 http://dx.doi.org/10.1016/j.psyneuen.2019.04.011

Ejemplares similares

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring study
por: Mullins, Niamh, et al.
Publicado: (2014)

The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study
por: Farmer, Anne, et al.
Publicado: (2004)

Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study
por: Hung, Chi-Fa, et al.
Publicado: (2014)

Prolactin, Estradiol and Testosterone Differentially Impact Human Hippocampal Neurogenesis in an In Vitro Model
por: Smeeth, Demelza M., et al.
Publicado: (2021)

Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder
por: Rucker, James J.H., et al.
Publicado: (2016)

Genome Wide Association Analysis of Copy Number Variation in Recurrent Depressive Disorder
por: Rucker, James J.H., et al.
Publicado: (2011)

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder
por: Hung, Chi-Fa, et al.
Publicado: (2015)

Telomere length and human hippocampal neurogenesis
por: Palmos, Alish B., et al.
Publicado: (2020)

Lithium treatment and human hippocampal neurogenesis
por: Palmos, Alish B., et al.
Publicado: (2021)

Inter-individual variation in genes governing human hippocampal progenitor differentiation in vitro is associated with hippocampal volume in adulthood
por: Powell, Timothy R., et al.
Publicado: (2017)

Genomewide Association Scan of Suicidal Thoughts and Behaviour in Major Depression
por: Schosser, Alexandra, et al.
Publicado: (2011)

The Role of Lipid Biomarkers in Major Depression
por: Parekh, Amy, et al.
Publicado: (2017)

The polygenic nature of telomere length and the anti-ageing properties of lithium
por: Coutts, Fiona, et al.
Publicado: (2018)

The genome‐wide expression effects of escitalopram and its relationship to neurogenesis, hippocampal volume, and antidepressant response
por: Powell, Timothy R., et al.
Publicado: (2017)

Polygenic interactions with environmental adversity in the aetiology of major depressive disorder
por: Mullins, N., et al.
Publicado: (2016)

Familiality and SNP heritability of age at onset and episodicity in major depressive disorder
por: Ferentinos, P., et al.
Publicado: (2015)

Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals()
por: Rivera, Margarita, et al.
Publicado: (2017)

Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables
por: Iniesta, Raquel, et al.
Publicado: (2018)

Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)
por: Ren, Hongyan, et al.
Publicado: (2018)

The polygenic risk for bipolar disorder influences brain regional function relating to visual and default state processing of emotional information
por: Dima, Danai, et al.
Publicado: (2016)

A systematic review of associations between functional MRI activity and polygenic risk for schizophrenia and bipolar disorder
por: Dezhina, Zalina, et al.
Publicado: (2018)

Methylenetetrahydrofolate Reductase Gene Variant (MTHFR C677T) and Migraine: A Case Control Study and Meta-analysis
por: Samaan, Zainab, et al.
Publicado: (2011)

Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning
por: Powell, Timothy R, et al.
Publicado: (2017)

por: Marshall, Catherine, et al.
Publicado: (2019)

A polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genotyping
por: Fabbri, Chiara, et al.
Publicado: (2020)

Telomere length as a predictor of emotional processing in the brain
por: Powell, Timothy R., et al.
Publicado: (2018)

Exploring the role of drug-metabolising enzymes in antidepressant side effects
por: Hodgson, Karen, et al.
Publicado: (2015)

Follow the money: how is medical school teaching funded?
por: O'Brien, Aileen, et al.
Publicado: (2021)

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts
por: Ward, Joey, et al.
Publicado: (2018)

Nomograms of human hippocampal volume shifted by polygenic scores
por: Janahi, Mohammed, et al.
Publicado: (2022)

Modulation of Adult Hippocampal Neurogenesis by Sleep: Impact on Mental Health
por: Navarro-Sanchis, Cristina, et al.
Publicado: (2017)

Polygenic dissection of the bipolar phenotype
por: Hamshere, M. L., et al.
Publicado: (2011)

Why looking at the whole hippocampus is not enough—a critical role for anteroposterior axis, subfield and activation analyses to enhance predictive value of hippocampal changes for Alzheimer’s disease diagnosis
por: Maruszak, Aleksandra, et al.
Publicado: (2014)

Prospects for using risk scores in polygenic medicine
por: Lewis, Cathryn M., et al.
Publicado: (2017)

Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the 5-HTTLPR
por: Strohmaier, Jana, et al.
Publicado: (2011)

PRSice: Polygenic Risk Score software
por: Euesden, Jack, et al.
Publicado: (2015)

Polygenic risk for Alzheimer's disease shapes hippocampal scene-selectivity
por: Chandler, Hannah L., et al.
Publicado: (2020)

Resveratrol: A Potential Hippocampal Plasticity Enhancer
por: Dias, Gisele Pereira, et al.
Publicado: (2016)

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression
por: Martin, Joanna, et al.
Publicado: (2021)

Polygenic risk scores: from research tools to clinical instruments
por: Lewis, Cathryn M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lu0qbhcf0olffsu3cdoftd6alf