Cargando…
Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients
Using liquid chromatography – mass spectrometry in combination with derivatisation chemistry we profiled the oxysterol and cholestenoic acid content of cerebrospinal fluid from patients with Alzheimer's disease (n = 21), vascular dementia (n = 11), other neurodegenerative diseases (n = 15, Lewy...
Autores principales: | Griffiths, William J., Abdel-Khalik, Jonas, Yutuc, Eylan, Roman, Gustavo, Warner, Margaret, Gustafsson, Jan-Åke, Wang, Yuqin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597949/ https://www.ncbi.nlm.nih.gov/pubmed/30578919 http://dx.doi.org/10.1016/j.freeradbiomed.2018.12.020 |
Ejemplares similares
-
Developing an Enzyme-Assisted Derivatization Method for Analysis of C(27) Bile Alcohols and Acids by Electrospray Ionization-Mass Spectrometry
por: Abdel-Khalik, Jonas, et al.
Publicado: (2019) -
Defective cholesterol metabolism in amyotrophic lateral sclerosis
por: Abdel-Khalik, Jonas, et al.
Publicado: (2017) -
Reduced Plasma Levels of 25-Hydroxycholesterol and Increased Cerebrospinal Fluid Levels of Bile Acid Precursors in Multiple Sclerosis Patients
por: Crick, Peter J., et al.
Publicado: (2016) -
Identification of 7α,24-dihydroxy-3-oxocholest-4-en-26-oic and 7α,25-dihydroxy-3-oxocholest-4-en-26-oic acids in human cerebrospinal fluid and plasma
por: Abdel-Khalik, Jonas, et al.
Publicado: (2018) -
Current trends in oxysterol research
por: Griffiths, William J., et al.
Publicado: (2016)