Medial Temporal Lobe Disconnection and Hyperexcitability Across Alzheimer’s Disease Stages

 The posteromedial cortex (PMC) and medial temporal lobes (MTL) are two brain regions particularly vulnerable in Alzheimer’s disease (AD). We have reviewed the spatiotemporal patterns of amyloid-β and tau accumulation, local MTL functional alterations and MTL-PMC network reconfiguration, and propose...

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Detalles Bibliográficos
Autores principales: Pasquini, Lorenzo, Rahmani, Farzaneh, Maleki-Balajoo, Somayeh, La Joie, Renaud, Zarei, Mojtaba, Sorg, Christian, Drzezga, Alexander, Tahmasian, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597961/
https://www.ncbi.nlm.nih.gov/pubmed/31259307
http://dx.doi.org/10.3233/ADR-190121

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