Targeted Protein Internalization and Degradation by ENDosome TArgeting Chimeras (ENDTACs)

[Image: see text] Targeted protein degradation has generated excitement in chemical biology and drug discovery throughout academia and industry. By hijacking the machinery responsible for protein degradation via the ubiquitin proteasome system (UPS), various cellular targets have been selectively de...

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Detalles Bibliográficos
Autores principales: Nalawansha, Dhanusha A., Paiva, Stacey-Lynn, Rafizadeh, Diane N., Pettersson, Mariell, Qin, Liena, Crews, Craig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598169/
https://www.ncbi.nlm.nih.gov/pubmed/31263767
http://dx.doi.org/10.1021/acscentsci.9b00224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598169/
https://www.ncbi.nlm.nih.gov/pubmed/31263767
http://dx.doi.org/10.1021/acscentsci.9b00224

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