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Targeted Protein Internalization and Degradation by ENDosome TArgeting Chimeras (ENDTACs)
[Image: see text] Targeted protein degradation has generated excitement in chemical biology and drug discovery throughout academia and industry. By hijacking the machinery responsible for protein degradation via the ubiquitin proteasome system (UPS), various cellular targets have been selectively de...
Autores principales: | Nalawansha, Dhanusha A., Paiva, Stacey-Lynn, Rafizadeh, Diane N., Pettersson, Mariell, Qin, Liena, Crews, Craig M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598169/ https://www.ncbi.nlm.nih.gov/pubmed/31263767 http://dx.doi.org/10.1021/acscentsci.9b00224 |
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