Effect of an educational intervention on the number potential drug-drug interactions

BACKGROUND: The objective of this study was to evaluate effect of an Educational intervention on the number Potential Drug-Drug Interactions in the Emergency Hospital. METHODS: The prevalence and structure of Major Drug-Drug Interactions at Emergency care Hospitals of Aktobe, Uralsk, Atyrau cities (...

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Autores principales: Mussina, Aigul Z., Smagulova, Gaziza A., Veklenko, Galina V., Tleumagambetova, Bibigul B., Seitmaganbetova, Nazgul A., Zhaubatyrova, Aigul A., Zhamaliyeva, Lazzat M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598212/
https://www.ncbi.nlm.nih.gov/pubmed/31297027
http://dx.doi.org/10.1016/j.jsps.2019.04.007
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author Mussina, Aigul Z.
Smagulova, Gaziza A.
Veklenko, Galina V.
Tleumagambetova, Bibigul B.
Seitmaganbetova, Nazgul A.
Zhaubatyrova, Aigul A.
Zhamaliyeva, Lazzat M.
author_facet Mussina, Aigul Z.
Smagulova, Gaziza A.
Veklenko, Galina V.
Tleumagambetova, Bibigul B.
Seitmaganbetova, Nazgul A.
Zhaubatyrova, Aigul A.
Zhamaliyeva, Lazzat M.
author_sort Mussina, Aigul Z.
collection PubMed
description BACKGROUND: The objective of this study was to evaluate effect of an Educational intervention on the number Potential Drug-Drug Interactions in the Emergency Hospital. METHODS: The prevalence and structure of Major Drug-Drug Interactions at Emergency care Hospitals of Aktobe, Uralsk, Atyrau cities (Kazakhstan) were studied (pharmacoepidemiological, cross-sectional study). Educational interventions were developed and implemented to improve pharmacotherapy in the Cardiology Department of the Aktobe Emergency Hospital, followed by an assessment of their effect. RESULTS: The effect of educational interventions was revealed, which led to a significant decrease in the indicators of drug interactions of the Major Drug-Drug Interactions by 18.2% (OR: 0.45; 95% CI, 0.25-to-0.82) in the cardiological patients of the Emergency Care Hospital of Aktobe city compared to the Regional Cardiology Center of Uralsk. CONCLUSION: The implementation of educational pharmacotherapy programs decreased the number of clinically significant drug interactions in the Cardiology Department of Emergency Hospitals.
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spelling pubmed-65982122019-07-11 Effect of an educational intervention on the number potential drug-drug interactions Mussina, Aigul Z. Smagulova, Gaziza A. Veklenko, Galina V. Tleumagambetova, Bibigul B. Seitmaganbetova, Nazgul A. Zhaubatyrova, Aigul A. Zhamaliyeva, Lazzat M. Saudi Pharm J Article BACKGROUND: The objective of this study was to evaluate effect of an Educational intervention on the number Potential Drug-Drug Interactions in the Emergency Hospital. METHODS: The prevalence and structure of Major Drug-Drug Interactions at Emergency care Hospitals of Aktobe, Uralsk, Atyrau cities (Kazakhstan) were studied (pharmacoepidemiological, cross-sectional study). Educational interventions were developed and implemented to improve pharmacotherapy in the Cardiology Department of the Aktobe Emergency Hospital, followed by an assessment of their effect. RESULTS: The effect of educational interventions was revealed, which led to a significant decrease in the indicators of drug interactions of the Major Drug-Drug Interactions by 18.2% (OR: 0.45; 95% CI, 0.25-to-0.82) in the cardiological patients of the Emergency Care Hospital of Aktobe city compared to the Regional Cardiology Center of Uralsk. CONCLUSION: The implementation of educational pharmacotherapy programs decreased the number of clinically significant drug interactions in the Cardiology Department of Emergency Hospitals. Elsevier 2019-07 2019-04-08 /pmc/articles/PMC6598212/ /pubmed/31297027 http://dx.doi.org/10.1016/j.jsps.2019.04.007 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Mussina, Aigul Z.
Smagulova, Gaziza A.
Veklenko, Galina V.
Tleumagambetova, Bibigul B.
Seitmaganbetova, Nazgul A.
Zhaubatyrova, Aigul A.
Zhamaliyeva, Lazzat M.
Effect of an educational intervention on the number potential drug-drug interactions
title Effect of an educational intervention on the number potential drug-drug interactions
title_full Effect of an educational intervention on the number potential drug-drug interactions
title_fullStr Effect of an educational intervention on the number potential drug-drug interactions
title_full_unstemmed Effect of an educational intervention on the number potential drug-drug interactions
title_short Effect of an educational intervention on the number potential drug-drug interactions
title_sort effect of an educational intervention on the number potential drug-drug interactions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598212/
https://www.ncbi.nlm.nih.gov/pubmed/31297027
http://dx.doi.org/10.1016/j.jsps.2019.04.007
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