Hemophagocytic lymphohistiocytosis associated with Epstein–Barr virus infection: case report and literature review

Hemophagocytic lymphohistiocytosis (HLH) is rare and life threatening syndrome. There are only a few reported cases of HLH with GI symptoms. We describe the case of an 18 months old boy who presented with a history of fever for 40 days, abdominal distention and hepatosplenomegaly. Abdominal x-ray sh...

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Autores principales: Bahabri, Saeed, Al Rikabi, Ammar C, Alshammari, Amjad O, Alturkestany, Sara I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598294/
https://www.ncbi.nlm.nih.gov/pubmed/31275547
http://dx.doi.org/10.1093/jscr/rjy096
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author Bahabri, Saeed
Al Rikabi, Ammar C
Alshammari, Amjad O
Alturkestany, Sara I
author_facet Bahabri, Saeed
Al Rikabi, Ammar C
Alshammari, Amjad O
Alturkestany, Sara I
author_sort Bahabri, Saeed
collection PubMed
description Hemophagocytic lymphohistiocytosis (HLH) is rare and life threatening syndrome. There are only a few reported cases of HLH with GI symptoms. We describe the case of an 18 months old boy who presented with a history of fever for 40 days, abdominal distention and hepatosplenomegaly. Abdominal x-ray showed a pneumoperitoneum. Urgent laparotomy was done which revealed an isolated cecal perforation. The histopathological findings in the subsequent resected bowel was HLH with evidence of positive EBV Barr infection.
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spelling pubmed-65982942019-07-03 Hemophagocytic lymphohistiocytosis associated with Epstein–Barr virus infection: case report and literature review Bahabri, Saeed Al Rikabi, Ammar C Alshammari, Amjad O Alturkestany, Sara I J Surg Case Rep Case Report Hemophagocytic lymphohistiocytosis (HLH) is rare and life threatening syndrome. There are only a few reported cases of HLH with GI symptoms. We describe the case of an 18 months old boy who presented with a history of fever for 40 days, abdominal distention and hepatosplenomegaly. Abdominal x-ray showed a pneumoperitoneum. Urgent laparotomy was done which revealed an isolated cecal perforation. The histopathological findings in the subsequent resected bowel was HLH with evidence of positive EBV Barr infection. Oxford University Press 2019-06-28 /pmc/articles/PMC6598294/ /pubmed/31275547 http://dx.doi.org/10.1093/jscr/rjy096 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Bahabri, Saeed
Al Rikabi, Ammar C
Alshammari, Amjad O
Alturkestany, Sara I
Hemophagocytic lymphohistiocytosis associated with Epstein–Barr virus infection: case report and literature review
title Hemophagocytic lymphohistiocytosis associated with Epstein–Barr virus infection: case report and literature review
title_full Hemophagocytic lymphohistiocytosis associated with Epstein–Barr virus infection: case report and literature review
title_fullStr Hemophagocytic lymphohistiocytosis associated with Epstein–Barr virus infection: case report and literature review
title_full_unstemmed Hemophagocytic lymphohistiocytosis associated with Epstein–Barr virus infection: case report and literature review
title_short Hemophagocytic lymphohistiocytosis associated with Epstein–Barr virus infection: case report and literature review
title_sort hemophagocytic lymphohistiocytosis associated with epstein–barr virus infection: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598294/
https://www.ncbi.nlm.nih.gov/pubmed/31275547
http://dx.doi.org/10.1093/jscr/rjy096
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