Rapid, low cost and sensitive detection of Calreticulin mutations by a PCR based amplicon length differentiation assay for diagnosis of myeloproliferative neoplasms

BACKGROUND: Calreticulin (CALR) gene mutations are currently recommended as biomarkers in diagnosis of patients with myeloproliferative neoplasms (MPN) with Jak2 V617F negative phenotype. Our aim was to establish a rapid, low cost and sensitive assay for identification of CALR gene mutations and to...

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Detalles Bibliográficos
Autores principales: Trung, Ngo Tat, Quyen, Dao Thanh, Hoan, Nghiem Xuan, Giang, Dao Phuong, Trang, Tran Thi Huyen, Velavan, Thirumalaisamy P., Bang, Mai Hong, Song, Le Huu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598322/
https://www.ncbi.nlm.nih.gov/pubmed/31248375
http://dx.doi.org/10.1186/s12881-019-0819-6

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