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Antitumor Effects of 8-Deoxylactucin in RB355 Human Retinoblastoma Cells Are Mediated via Apoptosis Induction, Reactive Oxygen Species Production, and Cell Cycle Arrest

BACKGROUND: Retinoblastoma is a rare malignancy arising from the immature cells of the retina, generally in children up to the age of 3 years. Here, we assessed the anticancer effects of a natural sesquiterpene lactone – 8-deoxylactucin – on the growth of the retinoblastoma RB355 and normal RPE cell...

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Detalles Bibliográficos
Autores principales:	Guiying, Tan, Yue, Li, Chao, Xiong, Jinhai, Yu, Qihua, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598461/ https://www.ncbi.nlm.nih.gov/pubmed/31219101 http://dx.doi.org/10.12659/MSM.914242

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