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Pharmacokinetic and Pharmacodynamic Integration and Resistance Analysis of Tilmicosin Against Mycoplasma gallisepticum in an In Vitro Dynamic Model
Mycoplasma gallisepticum is the major pathogen causing chronic respiratory disease in chickens. In the present study, we successfully established a one-compartment open model with first-order absorption to determine the relationship between tilmicosin pharmacokinetic and pharmacodynamic (PK/PD) indi...
Autores principales: | Huang, Zilong, Wu, Yuzhi, Zhou, Zichong, Xia, Xirui, Gu, Xiaoyan, Cai, Qinren, Shen, Xiangguang, Yang, Hong, Ding, Huanzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598723/ https://www.ncbi.nlm.nih.gov/pubmed/31293418 http://dx.doi.org/10.3389/fphar.2019.00670 |
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