Cargando…
Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA
To persist in microbial communities, the bacterial pathogen Legionella pneumophila must withstand competition from neighboring bacteria. Here, we find that L. pneumophila can antagonize the growth of other Legionella species using a secreted inhibitor: HGA (homogentisic acid). Unexpectedly, L. pneum...
Autores principales: | Levin, Tera C, Goldspiel, Brian P, Malik, Harmit S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598767/ https://www.ncbi.nlm.nih.gov/pubmed/31134893 http://dx.doi.org/10.7554/eLife.46086 |
Ejemplares similares
-
Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases
por: Fu, Jiaqi, et al.
Publicado: (2022) -
Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex
por: Durie, Clarissa L, et al.
Publicado: (2020) -
L. pneumophila resists its self-harming metabolite HGA via secreted factors and collective peroxide scavenging
por: Holland, Mische, et al.
Publicado: (2023) -
Community-acquired Pneumonia Secondary to Legionella pneumophila and Streptococcus pneumoniae: A Rare Co-infection
por: Beg, Moeezullah, et al.
Publicado: (2019) -
Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS
por: Sheedlo, Michael J, et al.
Publicado: (2021)