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Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools

BACKGROUND: Tamra Bhasma is derived from metallic copper that is recommended for different ailments of liver and spleen, dropsy, abdominal pain, heart disease, colitis, tumors, anemia, loss of appetite, tuberculosis, as well as eye problems. OBJECTIVES: The knowledge of crystallite size and active i...

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Autores principales: Singh, Rakesh Kr., Kumar, Sanjay, Aman, Abhay Kr., Karim, S.M., Kumar, Sunil, Kar, Manoranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598801/
https://www.ncbi.nlm.nih.gov/pubmed/29249635
http://dx.doi.org/10.1016/j.jaim.2017.06.012
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author Singh, Rakesh Kr.
Kumar, Sanjay
Aman, Abhay Kr.
Karim, S.M.
Kumar, Sunil
Kar, Manoranjan
author_facet Singh, Rakesh Kr.
Kumar, Sanjay
Aman, Abhay Kr.
Karim, S.M.
Kumar, Sunil
Kar, Manoranjan
author_sort Singh, Rakesh Kr.
collection PubMed
description BACKGROUND: Tamra Bhasma is derived from metallic copper that is recommended for different ailments of liver and spleen, dropsy, abdominal pain, heart disease, colitis, tumors, anemia, loss of appetite, tuberculosis, as well as eye problems. OBJECTIVES: The knowledge of crystallite size and active ingredients in Bhasma materials is limited restricting its use as nanomedicine in the modern era. Also, the 2015 Nobel prize in medicine has motivated many researchers towards traditional medicines. Therefore, the different chemical and physical properties of prepared Tamra Bhasma has been studied by modern experimental tools (XRD, VSM, SEM, FTIR and PL spectrometer) and the preliminary testing of Tamra Bhasma nanoparticles was examined on bacteria. MATERIALS AND METHODS: Bhasma is prepared by metals and minerals using three step procedures e.g. Shodhana, Bhavana and Marana. In the present work, for the preparation of Tamra Bhasma, pulverized copper wire was used and prepared by the principle of Puta (incineration) in an Electrical Muffle Furnace (EMF). RESULTS: X-ray diffraction analysis and scanning electron microscopy results revealed that the crystallite size of Bhasma powder was less than 100 nm and nanocrystallites of aglomerated size in micrometer. Magnetometer measurement supports its medicinal value. Photoluminescence (PL) properties of nanocrystalline Bhasma powder was investigated in UV-NIR region and shows luminescence in visible region. The antimicrobial study of Tamra Bhasma shows effectiveness on bacteria and, may be useful to control the bacterial infection disease. CONCLUSION: Scientific data obtained using modern scientific tools and evidence would support in utilizing the ancient Indian wisdom of Ayurveda for the development of newer drugs as a modern nanomedicine and in other possible technological applications.
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spelling pubmed-65988012019-07-11 Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools Singh, Rakesh Kr. Kumar, Sanjay Aman, Abhay Kr. Karim, S.M. Kumar, Sunil Kar, Manoranjan J Ayurveda Integr Med Original Research Article (Experimental) BACKGROUND: Tamra Bhasma is derived from metallic copper that is recommended for different ailments of liver and spleen, dropsy, abdominal pain, heart disease, colitis, tumors, anemia, loss of appetite, tuberculosis, as well as eye problems. OBJECTIVES: The knowledge of crystallite size and active ingredients in Bhasma materials is limited restricting its use as nanomedicine in the modern era. Also, the 2015 Nobel prize in medicine has motivated many researchers towards traditional medicines. Therefore, the different chemical and physical properties of prepared Tamra Bhasma has been studied by modern experimental tools (XRD, VSM, SEM, FTIR and PL spectrometer) and the preliminary testing of Tamra Bhasma nanoparticles was examined on bacteria. MATERIALS AND METHODS: Bhasma is prepared by metals and minerals using three step procedures e.g. Shodhana, Bhavana and Marana. In the present work, for the preparation of Tamra Bhasma, pulverized copper wire was used and prepared by the principle of Puta (incineration) in an Electrical Muffle Furnace (EMF). RESULTS: X-ray diffraction analysis and scanning electron microscopy results revealed that the crystallite size of Bhasma powder was less than 100 nm and nanocrystallites of aglomerated size in micrometer. Magnetometer measurement supports its medicinal value. Photoluminescence (PL) properties of nanocrystalline Bhasma powder was investigated in UV-NIR region and shows luminescence in visible region. The antimicrobial study of Tamra Bhasma shows effectiveness on bacteria and, may be useful to control the bacterial infection disease. CONCLUSION: Scientific data obtained using modern scientific tools and evidence would support in utilizing the ancient Indian wisdom of Ayurveda for the development of newer drugs as a modern nanomedicine and in other possible technological applications. Elsevier 2019 2017-12-15 /pmc/articles/PMC6598801/ /pubmed/29249635 http://dx.doi.org/10.1016/j.jaim.2017.06.012 Text en © 2017 Transdisciplinary University, Bangalore and World Ayurveda Foundation. Publishing Services by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research Article (Experimental)
Singh, Rakesh Kr.
Kumar, Sanjay
Aman, Abhay Kr.
Karim, S.M.
Kumar, Sunil
Kar, Manoranjan
Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools
title Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools
title_full Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools
title_fullStr Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools
title_full_unstemmed Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools
title_short Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools
title_sort study on physical properties of ayurvedic nanocrystalline tamra bhasma by employing modern scientific tools
topic Original Research Article (Experimental)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598801/
https://www.ncbi.nlm.nih.gov/pubmed/29249635
http://dx.doi.org/10.1016/j.jaim.2017.06.012
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