Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety

Herein (1)H and (13)C NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the li...

Descripción completa

Detalles Bibliográficos
Autores principales: Szőke, Kitti, Czompa, Attila, Lekli, István, Szabados-Fürjesi, Péter, Herczeg, Mihály, Csávás, Magdolna, Borbás, Anikó, Herczegh, Pál, Tósaki, Árpád
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598840/
https://www.ncbi.nlm.nih.gov/pubmed/31297426
http://dx.doi.org/10.1016/j.dib.2019.104146
Descripción
Sumario:Herein (1)H and (13)C NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the linsidomine-aspirin hybrid in oxidation reactions. This data article also concerns miscellaneous myocardial parameters of isolated rat hearts as a complementation of the tables shown in the paper entitled “A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety” Szoke et al., 2019. Column tables represent data of aorta flow, aortic pressure, derivated aortic pressure and cardiac output.

Ejemplares similares