Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety

Herein (1)H and (13)C NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the li...

Descripción completa

Detalles Bibliográficos
Autores principales: Szőke, Kitti, Czompa, Attila, Lekli, István, Szabados-Fürjesi, Péter, Herczeg, Mihály, Csávás, Magdolna, Borbás, Anikó, Herczegh, Pál, Tósaki, Árpád
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598840/
https://www.ncbi.nlm.nih.gov/pubmed/31297426
http://dx.doi.org/10.1016/j.dib.2019.104146
_version_ 1783430845123526656
author Szőke, Kitti
Czompa, Attila
Lekli, István
Szabados-Fürjesi, Péter
Herczeg, Mihály
Csávás, Magdolna
Borbás, Anikó
Herczegh, Pál
Tósaki, Árpád
author_facet Szőke, Kitti
Czompa, Attila
Lekli, István
Szabados-Fürjesi, Péter
Herczeg, Mihály
Csávás, Magdolna
Borbás, Anikó
Herczegh, Pál
Tósaki, Árpád
author_sort Szőke, Kitti
collection PubMed
description Herein (1)H and (13)C NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the linsidomine-aspirin hybrid in oxidation reactions. This data article also concerns miscellaneous myocardial parameters of isolated rat hearts as a complementation of the tables shown in the paper entitled “A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety” Szoke et al., 2019. Column tables represent data of aorta flow, aortic pressure, derivated aortic pressure and cardiac output.
format Online
Article
Text
id pubmed-6598840
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-65988402019-07-11 Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety Szőke, Kitti Czompa, Attila Lekli, István Szabados-Fürjesi, Péter Herczeg, Mihály Csávás, Magdolna Borbás, Anikó Herczegh, Pál Tósaki, Árpád Data Brief Chemistry Herein (1)H and (13)C NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the linsidomine-aspirin hybrid in oxidation reactions. This data article also concerns miscellaneous myocardial parameters of isolated rat hearts as a complementation of the tables shown in the paper entitled “A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety” Szoke et al., 2019. Column tables represent data of aorta flow, aortic pressure, derivated aortic pressure and cardiac output. Elsevier 2019-06-12 /pmc/articles/PMC6598840/ /pubmed/31297426 http://dx.doi.org/10.1016/j.dib.2019.104146 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Chemistry
Szőke, Kitti
Czompa, Attila
Lekli, István
Szabados-Fürjesi, Péter
Herczeg, Mihály
Csávás, Magdolna
Borbás, Anikó
Herczegh, Pál
Tósaki, Árpád
Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety
title Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety
title_full Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety
title_fullStr Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety
title_full_unstemmed Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety
title_short Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety
title_sort dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598840/
https://www.ncbi.nlm.nih.gov/pubmed/31297426
http://dx.doi.org/10.1016/j.dib.2019.104146
work_keys_str_mv AT szokekitti datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety
AT czompaattila datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety
AT lekliistvan datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety
AT szabadosfurjesipeter datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety
AT herczegmihaly datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety
AT csavasmagdolna datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety
AT borbasaniko datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety
AT herczeghpal datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety
AT tosakiarpad datasetonstructurestabilityandmyocardialeffectsofanewhybridaspirincontainingnitrogenmonoxidereleasingmolsidominemoiety

Ejemplares similares