Recent advances in the identification of the host factors involved in dengue virus replication

Dengue virus (DENV) belongs to the genus Flavivirus of the family Flaviviridae and it is primarily transmitted via Aedes aegypti and Aedes albopictus mosquitoes. The life cycle of DENV includes attachment, endocytosis, protein translation, RNA synthesis, assembly, egress, and maturation. Recent rese...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598876/
https://www.ncbi.nlm.nih.gov/pubmed/28124222
http://dx.doi.org/10.1007/s12250-016-3902-6
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author Wang, Yi
Zhang, Ping
author_facet Wang, Yi
Zhang, Ping
author_sort Wang, Yi
collection PubMed
description Dengue virus (DENV) belongs to the genus Flavivirus of the family Flaviviridae and it is primarily transmitted via Aedes aegypti and Aedes albopictus mosquitoes. The life cycle of DENV includes attachment, endocytosis, protein translation, RNA synthesis, assembly, egress, and maturation. Recent researches have indicated that a variety of host factors, including cellular proteins and microRNAs, positively or negatively regulate the DENV replication process. This review summarizes the latest findings (from 2014 to 2016) in the identification of the host factors involved in the DENV life cycle and Dengue infection. [Image: see text]
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spelling pubmed-65988762019-07-02 Recent advances in the identification of the host factors involved in dengue virus replication Wang, Yi Zhang, Ping Virol Sin Review Dengue virus (DENV) belongs to the genus Flavivirus of the family Flaviviridae and it is primarily transmitted via Aedes aegypti and Aedes albopictus mosquitoes. The life cycle of DENV includes attachment, endocytosis, protein translation, RNA synthesis, assembly, egress, and maturation. Recent researches have indicated that a variety of host factors, including cellular proteins and microRNAs, positively or negatively regulate the DENV replication process. This review summarizes the latest findings (from 2014 to 2016) in the identification of the host factors involved in the DENV life cycle and Dengue infection. [Image: see text] Springer Singapore 2017-01-24 /pmc/articles/PMC6598876/ /pubmed/28124222 http://dx.doi.org/10.1007/s12250-016-3902-6 Text en © Wuhan Institute of Virology, CAS and Springer Science+Business Media Singapore 2017
spellingShingle Review
Wang, Yi
Zhang, Ping
Recent advances in the identification of the host factors involved in dengue virus replication
title Recent advances in the identification of the host factors involved in dengue virus replication
title_full Recent advances in the identification of the host factors involved in dengue virus replication
title_fullStr Recent advances in the identification of the host factors involved in dengue virus replication
title_full_unstemmed Recent advances in the identification of the host factors involved in dengue virus replication
title_short Recent advances in the identification of the host factors involved in dengue virus replication
title_sort recent advances in the identification of the host factors involved in dengue virus replication
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598876/
https://www.ncbi.nlm.nih.gov/pubmed/28124222
http://dx.doi.org/10.1007/s12250-016-3902-6
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