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Dual pathways of tRNA hydroxylation ensure efficient translation by expanding decoding capability
In bacterial tRNAs, 5-carboxymethoxyuridine (cmo(5)U) and its derivatives at the first position of the anticodon facilitate non-Watson–Crick base pairing with guanosine and pyrimidines at the third positions of codons, thereby expanding decoding capabilities. However, their biogenesis and physiologi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599085/ https://www.ncbi.nlm.nih.gov/pubmed/31253794 http://dx.doi.org/10.1038/s41467-019-10750-8 |