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A structural model of the human serotonin transporter in an outward-occluded state

The human serotonin transporter hSERT facilitates the reuptake of its endogenous substrate serotonin from the synaptic cleft into presynaptic neurons after signaling. Reuptake regulates the availability of this neurotransmitter and therefore hSERT plays an important role in balancing human mood cond...

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Detalles Bibliográficos
Autores principales: Hellsberg, Eva, Ecker, Gerhard F., Stary-Weinzinger, Anna, Forrest, Lucy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599148/
https://www.ncbi.nlm.nih.gov/pubmed/31251747
http://dx.doi.org/10.1371/journal.pone.0217377

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