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DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response

Fanconi anemia (FA) is a multigenic disease of bone marrow failure and cancer susceptibility stemming from a failure to remove DNA crosslinks and other chromosomal lesions. Within the FA DNA damage response pathway, DNA-dependent monoubiquitinaton of FANCD2 licenses downstream events, while timely F...

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Detalles Bibliográficos
Autores principales:	Liang, Fengshan, Miller, Adam S., Longerich, Simonne, Tang, Caroline, Maranon, David, Williamson, Elizabeth A., Hromas, Robert, Wiese, Claudia, Kupfer, Gary M., Sung, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599204/ https://www.ncbi.nlm.nih.gov/pubmed/31253762 http://dx.doi.org/10.1038/s41467-019-10408-5

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