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An application of mixed-effect models to analyse contraceptive use in Malawian women

In Malawi, the current approach to family planning using contraceptive methods is individualised, yet studies have shown that variability in contraceptive-use still remains after accounting for it at individual and household levels. Therefore, this study assessed variability at higher levels such as...

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Autores principales: Makupe, Davis James, Kumwenda, Save, Kazembe, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599226/
https://www.ncbi.nlm.nih.gov/pubmed/31297237
http://dx.doi.org/10.1186/s40834-019-0088-y
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author Makupe, Davis James
Kumwenda, Save
Kazembe, Lawrence
author_facet Makupe, Davis James
Kumwenda, Save
Kazembe, Lawrence
author_sort Makupe, Davis James
collection PubMed
description In Malawi, the current approach to family planning using contraceptive methods is individualised, yet studies have shown that variability in contraceptive-use still remains after accounting for it at individual and household levels. Therefore, this study assessed variability at higher levels such as enumeration areas, districts and regions. Biasness of the estimates was addressed by the use of Bayesian approach. The study used 2015–16 Malawi Demographic Health Survey women data. After ascertaining the significance of association of all explanatory variables with contraceptive use, the top-down (backward) stepwise model selection method was followed in the Bayesian framework using Markov Chain Monte Carlo and defuse priors. Models were compared on the basis of Deviance Information Criteria and significance of parameter estimates was checked via credible intervals while that of cross-cluster variances was checked by examining their diagnostic plots. All the selected socio-demographic factors were strongly associated with contraceptive-use (p-value< 0.001). These factors include; region, place-of-residence, age, parity, education, occupation, marital-status and religion. It was also found that about 15 and 2.3% of the variation in contraceptive-use was attributed to enumeration area and district clustering, respectively. The single-level model underestimated the parameter estimates by at least 4% for both models. And parity-enumeration area, age-enumeration area and age-district random effects were significant in their respective models. It was also noted that most young women aged between 15 and 24 years were not using any contraceptive methods. The study indicated that there exist significant enumeration area and district heterogeneity on contraceptive use in Malawian women and that random-effect models are the most appropriate models other than single-level models. Thus family planning programs focusing on contraceptive-use should switch to inclusive approach and statistical analyses should consider including enumeration area and district heterogeneity while controlling for the above significant factors. Stakeholders may also consider encouraging young women to use contraceptive methods, if Malawi is to minimize problems due to overpopulation.
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spelling pubmed-65992262019-07-11 An application of mixed-effect models to analyse contraceptive use in Malawian women Makupe, Davis James Kumwenda, Save Kazembe, Lawrence Contracept Reprod Med Research In Malawi, the current approach to family planning using contraceptive methods is individualised, yet studies have shown that variability in contraceptive-use still remains after accounting for it at individual and household levels. Therefore, this study assessed variability at higher levels such as enumeration areas, districts and regions. Biasness of the estimates was addressed by the use of Bayesian approach. The study used 2015–16 Malawi Demographic Health Survey women data. After ascertaining the significance of association of all explanatory variables with contraceptive use, the top-down (backward) stepwise model selection method was followed in the Bayesian framework using Markov Chain Monte Carlo and defuse priors. Models were compared on the basis of Deviance Information Criteria and significance of parameter estimates was checked via credible intervals while that of cross-cluster variances was checked by examining their diagnostic plots. All the selected socio-demographic factors were strongly associated with contraceptive-use (p-value< 0.001). These factors include; region, place-of-residence, age, parity, education, occupation, marital-status and religion. It was also found that about 15 and 2.3% of the variation in contraceptive-use was attributed to enumeration area and district clustering, respectively. The single-level model underestimated the parameter estimates by at least 4% for both models. And parity-enumeration area, age-enumeration area and age-district random effects were significant in their respective models. It was also noted that most young women aged between 15 and 24 years were not using any contraceptive methods. The study indicated that there exist significant enumeration area and district heterogeneity on contraceptive use in Malawian women and that random-effect models are the most appropriate models other than single-level models. Thus family planning programs focusing on contraceptive-use should switch to inclusive approach and statistical analyses should consider including enumeration area and district heterogeneity while controlling for the above significant factors. Stakeholders may also consider encouraging young women to use contraceptive methods, if Malawi is to minimize problems due to overpopulation. BioMed Central 2019-06-27 /pmc/articles/PMC6599226/ /pubmed/31297237 http://dx.doi.org/10.1186/s40834-019-0088-y Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative abstmons Attribution 4.0 International License (http://creativeabstmons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative abstmons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Makupe, Davis James
Kumwenda, Save
Kazembe, Lawrence
An application of mixed-effect models to analyse contraceptive use in Malawian women
title An application of mixed-effect models to analyse contraceptive use in Malawian women
title_full An application of mixed-effect models to analyse contraceptive use in Malawian women
title_fullStr An application of mixed-effect models to analyse contraceptive use in Malawian women
title_full_unstemmed An application of mixed-effect models to analyse contraceptive use in Malawian women
title_short An application of mixed-effect models to analyse contraceptive use in Malawian women
title_sort application of mixed-effect models to analyse contraceptive use in malawian women
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599226/
https://www.ncbi.nlm.nih.gov/pubmed/31297237
http://dx.doi.org/10.1186/s40834-019-0088-y
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