Cargando…
A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma
BACKGROUND: Primary gastric squamous cell carcinoma is an extremely rare malignancy with few case reports reported so far in the current medical literature. Its incidence varies between 0.04 and 0.07% of all gastric malignancies with a male predominance in the sixth decade of life. It has been found...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599270/ https://www.ncbi.nlm.nih.gov/pubmed/31255175 http://dx.doi.org/10.1186/s12957-019-1657-x |
_version_ | 1783430928650993664 |
---|---|
author | Vailas, Michail G. Syllaios, Athanasios Hasemaki, Natasha Sotiropoulou, Maria Mpaili, Eustratia Sarlanis, Helen Felekouras, Evangelos Papalampros, Alexandros |
author_facet | Vailas, Michail G. Syllaios, Athanasios Hasemaki, Natasha Sotiropoulou, Maria Mpaili, Eustratia Sarlanis, Helen Felekouras, Evangelos Papalampros, Alexandros |
author_sort | Vailas, Michail G. |
collection | PubMed |
description | BACKGROUND: Primary gastric squamous cell carcinoma is an extremely rare malignancy with few case reports reported so far in the current medical literature. Its incidence varies between 0.04 and 0.07% of all gastric malignancies with a male predominance in the sixth decade of life. It has been found that this type of malignancy has a more aggressive behavior and associated poorer prognosis, when compared to gastric adenocarcinoma. Thus, the most appropriate management of this kind of neoplasia is still debatable due to the small number of reported cases. CASE PRESENTATION: We report the case of a 66-year-old man who underwent total gastrectomy with D2 lymphadenectomy for an ulcerative lesion in the fundus of the stomach that turned out to be primary gastric squamous cell carcinoma. CONCLUSIONS: Upon confirmation of this specific malignancy, the affected patients should be enrolled in strict follow-up protocols after curative surgery, since the risk for metastasis is high. Physicians should maintain high clinical suspicion in order to diagnose these tumors at an early stage, along with the need to rule out any other possible primary sites of squamous malignancy. |
format | Online Article Text |
id | pubmed-6599270 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-65992702019-07-11 A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma Vailas, Michail G. Syllaios, Athanasios Hasemaki, Natasha Sotiropoulou, Maria Mpaili, Eustratia Sarlanis, Helen Felekouras, Evangelos Papalampros, Alexandros World J Surg Oncol Case Report BACKGROUND: Primary gastric squamous cell carcinoma is an extremely rare malignancy with few case reports reported so far in the current medical literature. Its incidence varies between 0.04 and 0.07% of all gastric malignancies with a male predominance in the sixth decade of life. It has been found that this type of malignancy has a more aggressive behavior and associated poorer prognosis, when compared to gastric adenocarcinoma. Thus, the most appropriate management of this kind of neoplasia is still debatable due to the small number of reported cases. CASE PRESENTATION: We report the case of a 66-year-old man who underwent total gastrectomy with D2 lymphadenectomy for an ulcerative lesion in the fundus of the stomach that turned out to be primary gastric squamous cell carcinoma. CONCLUSIONS: Upon confirmation of this specific malignancy, the affected patients should be enrolled in strict follow-up protocols after curative surgery, since the risk for metastasis is high. Physicians should maintain high clinical suspicion in order to diagnose these tumors at an early stage, along with the need to rule out any other possible primary sites of squamous malignancy. BioMed Central 2019-06-29 /pmc/articles/PMC6599270/ /pubmed/31255175 http://dx.doi.org/10.1186/s12957-019-1657-x Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Vailas, Michail G. Syllaios, Athanasios Hasemaki, Natasha Sotiropoulou, Maria Mpaili, Eustratia Sarlanis, Helen Felekouras, Evangelos Papalampros, Alexandros A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma |
title | A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma |
title_full | A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma |
title_fullStr | A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma |
title_full_unstemmed | A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma |
title_short | A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma |
title_sort | type of neoplasia deadlier than gastric adenocarcinoma? report of a case of primary gastric squamous cell carcinoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599270/ https://www.ncbi.nlm.nih.gov/pubmed/31255175 http://dx.doi.org/10.1186/s12957-019-1657-x |
work_keys_str_mv | AT vailasmichailg atypeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT syllaiosathanasios atypeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT hasemakinatasha atypeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT sotiropouloumaria atypeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT mpailieustratia atypeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT sarlanishelen atypeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT felekourasevangelos atypeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT papalamprosalexandros atypeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT vailasmichailg typeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT syllaiosathanasios typeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT hasemakinatasha typeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT sotiropouloumaria typeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT mpailieustratia typeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT sarlanishelen typeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT felekourasevangelos typeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma AT papalamprosalexandros typeofneoplasiadeadlierthangastricadenocarcinomareportofacaseofprimarygastricsquamouscellcarcinoma |