Cargando…

“In sickness and in health” – how neutrophil extracellular trap (NET) works in infections, selected diseases and pregnancy

The discovery of the NET network (neutrophil extracellular trap) has revolutionized the perception of defense mechanisms used by neutrophils in infections and non-infectious states, as this mechanism proves the complexity of the ways in which neutrophils can act in the organism. The paper describes...

Descripción completa

Detalles Bibliográficos
Autores principales: Niedźwiedzka-Rystwej, Paulina, Repka, Weronika, Tokarz-Deptuła, Beata, Deptuła, Wiesław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599315/
https://www.ncbi.nlm.nih.gov/pubmed/31297037
http://dx.doi.org/10.1186/s12950-019-0222-2
Descripción
Sumario:The discovery of the NET network (neutrophil extracellular trap) has revolutionized the perception of defense mechanisms used by neutrophils in infections and non-infectious states, as this mechanism proves the complexity of the ways in which neutrophils can act in the organism. The paper describes the NET network and its participation in bacterial, viral, fungal and parasitic infections, both in a positive and a negative aspect. In addition, attention was paid to the participation of NETs in the course of autoimmune diseases, cancer, as well as its impact on pregnancy and fertility in mammals.