Cargando…

Evaluation of vector systems and promoters for overexpression of the acarbose biosynthesis gene acbC in Actinoplanes sp. SE50/110

BACKGROUND: Actinoplanes sp. SE50/110 is a natural producer of acarbose. It has been extensively studied in the last decades, which has led to the comprehensive analysis of the whole genome, transcriptome and proteome. First genetic and microbial techniques have been successfully established allowin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schaffert, Lena, März, Camilla, Burkhardt, Lisa, Droste, Julian, Brandt, David, Busche, Tobias, Rosen, Winfried, Schneiker-Bekel, Susanne, Persicke, Marcus, Pühler, Alfred, Kalinowski, Jörn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599336/ https://www.ncbi.nlm.nih.gov/pubmed/31253141 http://dx.doi.org/10.1186/s12934-019-1162-5

Ejemplares similares

The 4-α-Glucanotransferase AcbQ Is Involved in Acarbose Modification in Actinoplanes sp. SE50/110
por: Nölting, Sophia, et al.
Publicado: (2023)

The expression of the acarbose biosynthesis gene cluster in Actinoplanes sp. SE50/110 is dependent on the growth phase
por: Droste, Julian, et al.
Publicado: (2020)

Absence of the highly expressed small carbohydrate-binding protein Cgt improves the acarbose formation in Actinoplanes sp. SE50/110
por: Schaffert, Lena, et al.
Publicado: (2020)

Essentiality of the Maltase AmlE in Maltose Utilization and Its Transcriptional Regulation by the Repressor AmlR in the Acarbose-Producing Bacterium Actinoplanes sp. SE50/110
por: Schaffert, Lena, et al.
Publicado: (2019)

pSETT4, an Improved φC31-Based Integrative Vector System for Actinoplanes sp. SE50/110
por: Schaffert, Lena, et al.
Publicado: (2020)

The MalR type regulator AcrC is a transcriptional repressor of acarbose biosynthetic genes in Actinoplanes sp. SE50/110
por: Wolf, Timo, et al.
Publicado: (2017)

A maltose-regulated large genomic region is activated by the transcriptional regulator MalT in Actinoplanes sp. SE50/110
por: Droste, Julian, et al.
Publicado: (2020)

The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110
por: Schwientek, Patrick, et al.
Publicado: (2012)

Reconstruction and in silico analysis of an Actinoplanes sp. SE50/110 genome-scale metabolic model for acarbose production
por: Wang, Yali, et al.
Publicado: (2015)

Improving acarbose production and eliminating the by-product component C with an efficient genetic manipulation system of Actinoplanes sp. SE50/110
por: Zhao, Qinqin, et al.
Publicado: (2017)

Contribution of Nucleus Accumbens Core (AcbC) to Behavior Control during a Learned Resting Period: Introduction of a Novel Task and Lesion Experiments
por: Sato, Chika, et al.
Publicado: (2014)

Enhancement of acarbose production by genetic engineering and fed-batch fermentation strategy in Actinoplanes sp. SIPI12-34
por: Li, Zhenxin, et al.
Publicado: (2022)

Enhanced Production of Acarbose and Concurrently Reduced Formation of Impurity C by Addition of Validamine in Fermentation of Actinoplanes utahensis ZJB-08196
por: Xue, Ya-Ping, et al.
Publicado: (2013)

Physiology and Transcriptional Analysis of (p)ppGpp-Related Regulatory Effects in Corynebacterium glutamicum
por: Ruwe, Matthias, et al.
Publicado: (2019)

Biosynthesis of antibiotic chuangxinmycin from Actinoplanes tsinanensis
por: Shi, Yuanyuan, et al.
Publicado: (2018)

Generating Individual Patient Preferences for the Treatment of Osteoarthritis Using Adaptive Choice-Based Conjoint (ACBC) Analysis
por: Al-Omari, Basem, et al.
Publicado: (2017)

Unconventional secretion of Acb1 is mediated by autophagosomes
por: Duran, Juan M., et al.
Publicado: (2010)

Genome Sequence of Sinorhizobium meliloti Rm41
por: Weidner, Stefan, et al.
Publicado: (2013)

Visualizing post genomics data-sets on customized pathway maps by ProMeTra – aeration-dependent gene expression and metabolism of Corynebacterium glutamicum as an example
por: Neuweger, Heiko, et al.
Publicado: (2009)

CUPS provide a handle on Acb1 secretion
por: Short, Ben
Publicado: (2011)

Differential Effects of D-Cycloserine and ACBC at NMDA Receptors in the Rat Entorhinal Cortex Are Related to Efficacy at the Co-Agonist Binding Site
por: Lench, Alex M., et al.
Publicado: (2015)

Actinoplanes teichomyceticus ATCC 31121 as a cell factory for producing teicoplanin
por: Taurino, Carlo, et al.
Publicado: (2011)

Characterization of the genes responsible for rubber degradation in Actinoplanes sp. strain OR16
por: Gibu, Namiko, et al.
Publicado: (2020)

Acarbose is again on the stage
por: Altay, Mustafa
Publicado: (2022)

Complete genome sequence of the motile actinomycete Actinoplanes missouriensis 431(T) (= NBRC 102363(T))
por: Yamamura, Hideki, et al.
Publicado: (2012)

Draft Genome Sequence of Teicoplanin-Producing Strain Actinoplanes teichomyceticus CPCC 203265
por: Li, Xingxing, et al.
Publicado: (2019)

Identification and Functional Characterization of Small Alarmone Synthetases in Corynebacterium glutamicum
por: Ruwe, Matthias, et al.
Publicado: (2017)

Reactive oxygen species triggers unconventional secretion of antioxidants and Acb1
por: Cruz-Garcia, David, et al.
Publicado: (2020)

Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion
por: Trost, Eva, et al.
Publicado: (2010)

Effect of Ball Screen and One-on-One on the Level of Opposition and Effectiveness of Shots in the ACB
por: Serna, Jorge, et al.
Publicado: (2021)

Exploration of suitable pharmacodynamic parameters for acarbose bioequivalence evaluation: A series of clinical trials with branded acarbose
por: Huang, Jie, et al.
Publicado: (2020)

Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum
por: Kulis-Horn, Robert K, et al.
Publicado: (2014)

Functional Characterization of a Small Alarmone Hydrolase in Corynebacterium glutamicum
por: Ruwe, Matthias, et al.
Publicado: (2018)

The MarR-Type Regulator MalR Is Involved in Stress-Responsive Cell Envelope Remodeling in Corynebacterium glutamicum
por: Hünnefeld, Max, et al.
Publicado: (2019)

Draft Genome Sequence of an Endophytic Actinoplanes Species, Encoding Uncommon trans-Acyltransferase Polyketide Synthases
por: Centeno-Leija, Sara, et al.
Publicado: (2016)

On the potential of acarbose to reduce cardiovascular disease
por: Standl, Eberhard, et al.
Publicado: (2014)

CoryneCenter – An online resource for the integrated analysis of corynebacterial genome and transcriptome data
por: Neuweger, Heiko, et al.
Publicado: (2007)

Extensive Reannotation of the Genome of the Model Streptomycete Streptomyces lividans TK24 Based on Transcriptome and Proteome Information
por: Droste, Julian, et al.
Publicado: (2021)

Evaluation of the pharmacokinetics of metformin and acarbose in the common marmoset
por: Fernandez, Elizabeth, et al.
Publicado: (2019)

Acarbose improved survival for Apc(+/Min) mice
por: Dodds, Sherry G., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2ru96s44nl6g9qjmbkl7080k3b